INTERACTION BETWEEN CHLORDIAZEPOXIDE AND PROPANIDID

The interaction of suxamethonium with propanidid and thiopentone.

An investigation was carried out in adults aged 20-60 years comparing the interaction of propanidid or thiopentone with the muscle relaxant suxamethonium. An attempt was made to correlate the apnoea time with the incidence and severity of muscle pains. No correlation was found between the apnoea times and the incidence of muscle pains. The overall incidence of muscle pains was 19 per cent. The ...

Propanidid, an intravenous anesthetic agent.

Hypotensive reaction after propanidid and atropine.

SIR,-I wish to report reactions during anaesthesia using propanidid. The patients were two children aged 12 and 4 years, each undergoing an operation for the evacuation of pus, one from a submandibular abscess, the other from a pelvic abscess. Both children were ill as a result of these conditions, but not severely toxic or with a high fever. In each case the child received the recommended dose...

Interaction between Intestinal Microbiota and Serotonin Metabolism

Gut microbiota regulates the production of signaling molecules, such as serotonin or 5-Hydroxytryptamine: 5-HT in the host. Serotonin is a biogenic amine that acts as a neurotransmitter in the gut and brain. There is a perfect interaction between human gastrointestinal microbiota and the serotonin system. The gut microbiota plays an important role in the serotonin signaling pathways through the...

Chlordiazepoxide dichloro­methane monosolvate

IN THE TITLE COMPOUND (SYSTEMATIC NAME 7-chloro-2-methyl-amino-5-phenyl-3H-1,4-benzodiazepine 4-oxide dichloro-meth-ane monosolvate), C(16)H(14)ClN(3)O·CH(2)Cl(2), the seven-membered ring adopts a boat conformation with the CH(2) group as the prow and the two aromatic C atoms as the stern. The dihedral angle between the benzene rings is 75.25 (6)°. The crystal structure features centrosymmetric...